I agree that the comments are deeply troubling, but I think you're now doing the dehumanization thing in reverse, because there is a very obvious, and widely stated, alternative position.
That is: trans people are people and have all the rights that people always should, but "transness" is a made-up category, no different than membership in a cult, or adherence to some other incorrect belief like that one is actually a Pokemon.
This position is wrong. It is hurtful. It undermines the rights and safety of trans people.
But it is not genocidal any more than a ban on Swifties is genocidal, because the fundamental story is that there's a group of people at least most of whom are under the sway of some false belief, not a group of people who are fundamentally subhuman or evil. (A subset that they designate as "groomers" they do identify as legitimately evil--that's a different and more dangerous kind of charge, but it's not what's going on here.) The idea is invalid, not the people. This is not to say that banning ideas is a good move either, but it's a different problem from genocide.
Lumping the relatively small group of genuinely violence-endorsing ideologues in with a far larger group of people who are intolerant and rather lacking in understanding is, I think, actually profoundly dangerous because it gives space for the danger to grow. It makes the latter group justifiably feel demonized and dehumanized for having intent to commit near-universally abhorred acts (which the former group actually does have, but the latter does not). And everyone on that side gets used to thinking, "Haha, genocide, whatever, right." Also, "well, then trans people are committing genocide against Christians" (because they want to make it illegal to uphold supposedly-Christian values).
As Syndrome from the Incredibles might say, "If everything is genocide, then nothing is."
And if we accept that, we have lost our biggest advantage against actual genocide and other grave atrocities.
There is plenty of ammunition against Knowles without having to provoke that danger.